Read e-book online Aluminum and renal failure PDF

By Marc E. de Broe, Patrick C. D’Haese (auth.), Marc E. de Broe, Jack W. Coburn (eds.)

ISBN-10: 0792303474

ISBN-13: 9780792303473

ISBN-10: 9400918682

ISBN-13: 9789400918689

ISBN-10: 9401073333

ISBN-13: 9789401073332

` ... the fabric awarded offers helpful details about the organic results and scientific syndromes linked to aluminum publicity. This quantity may be worthwhile for college students and nephrologists who're attracted to furthering their knowing of the area.'
Dialysis and Transplantation, 20/1, January 1991

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In a 40-day balance study in which volunteers were administered Al as the lactate in fruit juice, Greger and Baier [23] also found asignificant increase in serum concentrations and urinary excretion, but no indication was found for any retention of AI. Brown et ai. [24], studying absorption from ace glut amide aluminum, also found that the Al absorbed from this complex was rapidly excreted in the urine and the feces. Intake of AI-containing antacids may have an effect on the metabolism of other minerals than Al as well.

39. Simon P, Allain P, Mauras Y, Ang KS, 1982: Hyperaluminemia test (HAT) by desferrioxamine (DFA) for the determination of tissue aluminum overload (TAO) in hemodialysis patients. Aggravating factor of chronic injections by B and non-A, non-B virus. Kidney Int 21: 900. 40. Sjogren B, Lundberg I, Lidums V, 1983: Aluminium in the blood and urine of industrially exposed workers. Br J Ind Med 40: 301. 41. Skalsky HL, Carchman RA, 1983: Aluminum Homeostasis in man. J Am Coli Toxicol2: 405. 42. Slanina P, Frech W, Bernhardson A, Cedergren A, Mattsson P, 1985: Infuence of dietary factors on aluminum absorption and retention in the brain and bone of rats.

In spite of decrease in serum phosphate and a concomitant rise in serum calcium, the PTH levels remained to be high, whereas serum Al rose significantly. In later studies, reviewed by Slatopolsky [30], decreased PTH levels were observed in patients with Al accumulation. It is as yet unclear whether this is a result of a direct effect of Al on the parathyroid glands, or because serum calcium concentrations are relatively high in this group of patients. In any case, the interaction between AI, PTH and calcium metabolism remains to be elucidated in detail in future studies.

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Aluminum and renal failure by Marc E. de Broe, Patrick C. D’Haese (auth.), Marc E. de Broe, Jack W. Coburn (eds.)


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