By John G. Bartlett
Designed to supply easy accessibility to the criteria with which to struggle infectious disorder by means of targeting choice, right doses, bills, and negative effects of antimicrobial brokers, the 2004 notebook of Infectious disorder treatment attracts largely from suggestions made via the facilities for affliction keep an eye on, the clinical Letter, the yankee sanatorium Formulary provider, and the AMA's Drug reviews. Tabular fabric has been up to date to incorporate all newly licensed antibiotics, in addition to new suggestions for administration.
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Extra resources for 2004 Pocket Book of Infectious Disease Therapy
Standard dose Gentamicin and tobramycin: 5–6 mg/kg/d (some use 4–7 mg/kg/d) Amikacin and streptomycin: 15–20 mg/kg/d 2. 5 Cg/mL Amikacin:<5 Cg/mL 3. 41 C. 5 —1–3 g q4–6h Usual usual Usual Usual 1–2 g IV q8h 1–2 g IV q 12h g q6h Ampicillin-sulbactam Renal 1 8–12 — 1–2 g q6h 1–2 g IV q8h 1–2 g IV q8h 1–2 g IVq12h Atovaquone Gut 70 70 750 mg bid susp — Usual Usual Unknown Atovaquone +proguanil Urinary 70 ? 7 ? 4 ? 25–1 g q6h Usual Usual Usual Chloroquine Renal and metabolized 48–120 ? 5–1 g q12h Cycloserine Renal 8–12 ?
Telithromycin: No dose adjustment. Ticarcillin: For patients with hepatic dysfunction and creatinine clearance <10 mL/min, give 2 g/d IV in one or two doses. 1 g) followed by 2 g once daily. Trovafloxacin: For hepatic failure, adjust by indicated dose—indicated dose 300 mg/d IV, use 200 mg/d; indicated dose 200 mg/d IV or po, use 100 mg/d; indicated dose 100 mg/d, use 100 mg/d. Voriconazole: Mild to moderate hepatic insufficiency—6 mg/kg IV q12h × 2, then 2 mg/kg IV q12h. Editors: Bartlett, John G.
Cefoperazone: Maximum dose is 4 g/d; if higher, monitor levels; with coexisting renal impairment maximum dose is 1–2 g/d. Ceftriaxone: Maximum daily dose of 2 g with severe hepatic and renal impairment. Chloramphenicol: Use with caution with renal and/or hepatic failure; monitor serum levels to achieve levels of 5–20 :g/mL. Clindamycin: Dose reduction recommended only for severe hepatic failure. Daptomycin: No dose adjustment. Fluoroquinolones: Use standard dose except with trovafloxacin (see below).
2004 Pocket Book of Infectious Disease Therapy by John G. Bartlett